Jan Drexler und Hopfner Kp - Info zur Person

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Hopfner Lab - Structural Molecular Biology - Gene Center ...

www.genzentrum.uni-muenchen.de

Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Nature Sep 21;549(7672): doi: nature Epub Sep 13. PubMed. Structural mechanism of cytosolic DNA sensing by cGAS. Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP. Nature Jun ...

Innate Immunity - Gene Center Munich - LMU Munich

www.genzentrum.uni-muenchen.de

Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Nature Sep 21;549(7672): doi: nature Epub Sep 13. PubMed. ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.

Publications - GRK LMU Munich

www.grk1721.genzentrum.uni-muenchen.de

Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Nature Sep 21;549(7672): doi: nature Epub Sep 13. PubMed. Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization.

ImmunoSensation / The Immune Sensory System » Publications

www.immunosensation.de

Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Cytosolic DNA arising from intracellular pathogens triggers a powerful innate immune response. It is sensed by cyclic GMP-AMP synthase (cGAS), which elicits the production of type I interferons by generating the second messenger 2'3'-cyclic-GMP-AMP (cGAMP ...

Publications - Human Biology & BioImaging - LMU Munich

www.bioimaging.bio.lmu.de

Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V and Hopfner KP (2017). cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. Nature, 549, PubMed. Cremer M, Schmid VJ, Kraus F, Markaki Y, Hellmann I, Maiser A, Leonhardt H, John S, Stamatoyannopoulos J and Cremer T (2017). Initial high ...

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